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Sarah was diagnosed with CF from inheriting two defective chromosome 7 with the gene responsible for CF [one from each parent]
Sarah and her husband are allowed to have children, but it is taking them a very long time. Yet, they are not giving up! Sarah being diagnosed [homozygous dominant] and Jerry being a homozygous recessive know their child is going to be 100% not diagnosed with CF but still a heterozygous.
Because our parents are both heterozygous, there was a 50% chance their children were going to be heterozygous, 25% homozygous recessive and 25% homozygous dominant. My brother Josh and I are both heterozygous, while Sarah fell into the 25% homozygous dominant category. If Josh and I both marry homozygous recessive indiviudals, we have a 50% chance our children will be heterozygous and a 50% chance of them being homozygous recessive. However, if we marry individuals who are diagnosed with CF, our children have 50% chance of being heterozygous and a 50% chance of them being homozygous dominant and inheriting CF.
This is my last blog.. upsetting, I know. I hope you all enjoyed listening to my sister’s journey battling with Cystic Fibrosis in my point of view. Remember to keep her in your prayers. Thank you.